Author

D. Alvarez-Villanueva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2

Frequent Co-Authors

A. Bigas· 3 shared A. Villanueva· 3 shared j. Bertran· 3 shared L. Espinosa· 3 shared A. VIDAL· 2 shared C. Santos· 2 shared L. Sole· 2 shared M. Maqueda· 2 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCell Biology

A. Bigas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivJul 28, 2023

Chromatin activity of IκBα mediates the exit from naïve pluripotency

L. G. Palma, D. Alvarez-Villanueva, M. Maqueda…·A. Bigas

This study shows that IκBα's chromatin activity, not its NF-κB signaling role, is critical for exiting naïve pluripotency in embryonic stem cells.

DOI 10.7554/elife.102784

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 21, 2023

Separation-of-function mutants reveal the NF-κB-independent involvement of IκBα in the regulation of stem cell and oncogenic programs

D. Alvarez-Villanueva, L. Galan, j. Bertran…·L. Espinosa

This paper identifies IκB's NF-κB-independent role in stem cell and oncogenic programs using separation-of-function mutants.

DOI 10.1101/2023.06.21.545928

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 13, 2023

IKK1 kinase coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy

L. Espinosa, I. Pecharroman Ruiz, L. Sole…·R. salazar

This study identifies IKK1's role in coordinating BRD4 and JAK/STAT signaling to resist DNA damage-based therapy in colorectal cancer.

DOI 10.1101/2023.06.13.544711

humanDNA methylation

𝕏 PostBluesky

Cancer BiologybioRxivFeb 6, 2023

Paradoxical activation of oncogenic signaling as a cancer treatment strategy

M. H. Dias, A. Friskes, S. Wang…·R. Bernards

This study shows that inhibiting PP2A and WEE1 together can kill colon cancer cells by causing DNA replication collapse and cell death, and that resistance to this treatment suppresses tumor growth.

DOI 10.1158/2159-8290.cd-23-0216

humanbulk RNA-seq

𝕏 PostBluesky