Modeling alcoholic liver disease in a human Liver-Chip
J. C. Nawroth, D. B. Petropolis, D. V. Manatakis, T. I. Maulana, G. Burchett, K. Schluender, A. Witt, A. Shukla, G. Hamilton, E. Seki, S. Lu, K. Karalis
This paper develops a human ALD Liver-Chip to model alcohol-induced liver injury, showing it recapitulates FLD markers and enables multimodal profiling of clinically relevant endpoints.
bioRxiv · Jul 14, 2020 · PreprintBioengineering