Author

D. Boucher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. H. Chan· 1 shared D. Lagos· 1 shared H. Pouillevet· 1 shared J. B. Von Pein· 1 shared J. W. Pitchford· 1 shared K. Schroder· 1 shared K. Vezyrgiannis· 1 shared L. I. Labzin· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. H. Chan

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

A. H. Chan, K. Vezyrgiannis, J. B. Von Pein, X. Wang, L. I. Labzin, D. Boucher, K. Schroder

This study identifies that caspase-4 dimerisation and D289 auto-processing enable direct cleavage of pro-IL-1β, independent of the NLRP3 inflammasome.

bioRxiv · Jan 5, 2023Immunology

Mathematical modelling of activation-induced heterogeneity reveals cell state transitions underpinning macrophage responses to LPS

S. Dey, D. Boucher, J. W. Pitchford, D. Lagos

The paper uses mathematical modeling and single-cell data to show how macrophage heterogeneity under LPS drives primary and secondary responses, with hypo-responsiveness linked to state transitions in a 3- or 4-state model.

bioRxiv · Sep 19, 2021 · PreprintImmunology

Inflammatory and oxidative status in European captive black rhinoceroses: a link with Iron Overload Disorder?

H. Pouillevet, N. Soetart, D. Boucher, R. Wedlarski, L. Jaillardon

This study compares inflammatory and oxidative status between black and white rhinoceroses, finding higher iron levels and oxidative stress markers in black rhinoceroses, possibly linked to Iron Overload Disorder.

bioRxiv · Mar 26, 2020Zoology