Author

J. B. von Pein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:E. coli· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. H. Chan· 1 shared A. S. Amiss· 1 shared B. J. Currie· 1 shared D. Boucher· 1 shared D. J. Craik· 1 shared J. R. Webb· 1 shared K. Schroder· 1 shared K. Vezyrgiannis· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. H. Chan

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2 papers

Recent·Most cited

ImmunologybioRxivJan 5, 2023

Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

A. H. Chan, K. Vezyrgiannis, J. B. Von Pein…·K. Schroder

This study identifies that caspase-4 dimerisation and D289 auto-processing enable direct cleavage of pro-IL-1β, independent of the NLRP3 inflammasome.

DOI 10.26508/lsa.202301908

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivJun 27, 2021

Modified defence peptides from horseshoe crab target and kill bacteria inside host cells

A. S. Amiss, J. B. von Pein, J. R. Webb…·N. Lawrence

This study identifies modified antimicrobial peptides from horseshoe crabs that effectively kill bacteria, including UPEC, both extracellularly and intracellularly, with reduced toxicity to mammalian cells.

DOI 10.1007/s00018-021-04041-z

E. coliproteomics

𝕏 PostBluesky