Author

D. De Vlieger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 1 Assay:protein structure· 1 Organism:rat· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

B. Schepens· 2 shared K. Roose· 2 shared X. Saelens· 2 shared B. S. Graham· 1 shared B. Vanmechelen· 1 shared C. De Keyzer· 1 shared D. Jochmans· 1 shared D. Schols· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

B. Schepens

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

R. Boudewijns, H. J. Thibaut, S. J. F. Kaptein, R. Li, V. Vergote, L. Seldeslachts, C. De Keyzer, L. Bervoets, S. Sharma, J. Van Weyenbergh, L. Liesenborghs, J. Ma, S. Jansen, D. Van Looveren, T. Vercruysse, , X. Saelens

This study shows that STAT2 signaling both restricts SARS-CoV-2 spread and causes severe pneumonia in infected hamsters.

bioRxiv · Apr 23, 2020 · PreprintMicrobiology

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-domain Camelid Antibodies

D. Wrapp, D. De Vlieger, K. S. Corbett, G. M. Torres, W. Van Breedam, K. Roose, L. van Schie, VIB-CMB COVID-19 Response Team, M. Hoffmann, S. Pöhlmann, B. S. Graham, N. Callewaert, B. Schepens, X. Saelens, J. S. McLellan

This study isolates and characterizes VHH antibodies that neutralize MERS-CoV, SARS-CoV-1, and SARS-CoV-2 by blocking receptor binding, with structural insights into their epitopes and cross-reactivity.

bioRxiv · Mar 26, 2020Microbiology