Author

L. Liesenborghs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:mouse· 3 Organism:rat· 3 Assay:spatial transcriptomics· 1 Approach:statistical model· 1 Research Focus:synaptic & neural circuits· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

H. J. Thibaut· 3 shared L. Delang· 3 shared C. De Keyzer· 2 shared E. Heylen· 2 shared J. Neyts· 2 shared J. Rocha-Pereira· 2 shared K. Dallmeier· 2 shared L. Bervoets· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

H. J. Thibaut

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

All Staphylococcus aureus bacteraemia strains have the potential to cause infective endocarditis: results of GWAS and experimental animal studies

S. Bastien, S. Meyers, W. Salgado-Pabon, S. Giulieri, J.-P. Rasigade, L. Liesenborghs, K. J. Kinney, F. Couzon, P. Martin-Simoes, V. Le Moing, X. M. Duval, N. E. Holmes, N. E. Bruun, R. Skov, B. P. Howden, , F. Vandenesch

This study shows that all Staphylococcus aureus bacteraemia strains can cause infective endocarditis, as no genetic differences were found between IE and non-IE strains using GWAS and experimental models.

bioRxiv · May 16, 2022 · PreprintMicrobiology

Biodistribution and Environmental Safety of a Live-attenuated YF17D-vectored SARS-CoV-2 Vaccine Candidate

L.-H. Li, L. Liesenborghs, L. Wang, M. Lox, M. B. Yakass, S. Jansen, A. L. Rosales Rosas, X. Zhang, H. J. Thibaut, D. Teuwen, J. Neyts, L. Delang, K. Dallmeier

This study evaluates the safety and biodistribution of a YF17D-vectored SARS-CoV-2 vaccine candidate in hamsters, showing improved safety compared to parental YF17D.

bioRxiv · Jan 24, 2022Microbiology

Antiviral treatment of SARS-CoV-2-infected hamsters reveals a weak effect of favipiravir and a complete lack of effect for hydroxychloroquine

S. J. Kaptein, S. Jacobs, L. Langendries, L. Seldeslachts, S. ter Horst, L. Liesenborghs, B. Hens, V. Vergote, E. Heylen, E. Maas, C. De Keyzer, L. Bervoets, J. Rymenants, T. Van Buyten, H. J. Thibaut, , L. Delang

This study evaluates the antiviral effects of favipiravir and hydroxychloroquine in SARS-CoV-2-infected hamsters, finding limited efficacy for both drugs.

bioRxiv · Jun 19, 2020 · PreprintMicrobiology

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

R. Boudewijns, H. J. Thibaut, S. J. F. Kaptein, R. Li, V. Vergote, L. Seldeslachts, C. De Keyzer, L. Bervoets, S. Sharma, J. Van Weyenbergh, L. Liesenborghs, J. Ma, S. Jansen, D. Van Looveren, T. Vercruysse, , X. Saelens

This study shows that STAT2 signaling both restricts SARS-CoV-2 spread and causes severe pneumonia in infected hamsters.

bioRxiv · Apr 23, 2020 · PreprintMicrobiology