Comparative infectivity and pathogenesis of emerging SARS-CoV-2 variants in Syrian hamsters
R. Abdelnabi, R. Boudewijns, C. S.-Y. Foo, L. Seldeslachts, L. Sanchez-Felipe, X. Zhang, L. Delang, P. Maes, S. J. F. Kaptein, B. Weynand, G. Vande Velde, J. Neyts, K. Dallmeier
This study compares the infectivity and pathogenicity of SARS-CoV-2 variants B.1.1.7 and B.1.351 to early 2020 strains in Syrian hamsters, finding similar disease outcomes but stronger proinflammatory cytokine elevation in B.1.1.7 infections.
bioRxiv · Feb 26, 2021Microbiology