Author

O. Eickelberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. Sengupta· 2 shared C. H. Mayr· 2 shared G. Burgstaller· 2 shared H. B. Schiller· 2 shared M. Koenigshoff· 2 shared M. Lindner· 2 shared A. Doryab· 1 shared A. Guenther· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

A. Sengupta

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Optimal transport for mapping senescent cells in spatial transcriptomics

N. D. Nguyen, L. Rosas, T. Khaliullin, P. Jiang, E. Hasanaj, J. A. Ovando, M. Bueno, M. Konigshoff, O. Eickelberg, M. Rojas, A. L. Mora, J. Lugo-Martinez, Z. Bar-Joseph

The paper develops scDOT, a method combining spatial transcriptomics and single-cell RNA-seq with optimal transport to improve spatial mapping of senescent cells and identify novel genes involved in cell-cell interactions.

bioRxiv · Aug 16, 2023Cell Biology

Fibroblasts-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis

O. Burgy, C. H. Mayr, B. Ballester Llobell, A. Sengupta, D. Schenesse, C. Coughlan, T. Parimon, P. Chen, M. Lindner, A. Hilgendorff, M. Mann, A. O. Yildirim, O. Eickelberg, M. Lehmann, H. B. Schiller, , M. Königshoff

This study identifies fibroblast-derived extracellular vesicles containing SFRP1 that contribute to pulmonary fibrosis and suggests SFRP1 as a therapeutic target.

bioRxiv · Dec 22, 2022Cell Biology

Autocrine Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts

C. H. Mayr, A. Sengupta, M. Ansari, J. Pestoni, P. Ogar, I. Angelidis, A. Liontos, J. A. Rodriguez, N. J. Lang, M. Strunz, S. Ashgarpour, D. Gonzalez, M. Gerckens, B. Oehrle, V. Viteri, , H. B. Schiller

The paper identifies Sfrp1 as an autocrine inhibitor of fibroblast invasion during lung fibrosis by analyzing fibroblast states and signaling pathways in mouse lung regeneration.

bioRxiv · Jul 11, 2022Cell Biology

Single cell transcriptome mapping identifies a local innate B cell population driving local antibody production and chronic rejection after lung transplantation

N. F. Smirnova, K. A. Riemondy, S. Collins, K. N. Patel, C. Cool, M. Koenigshoff, N. S. Sharma, O. Eickelberg

The paper identifies a local innate B cell population that drives antibody production and chronic rejection in lung transplants using single-cell transcriptomics.

bioRxiv · Feb 16, 2021 · PreprintPhysiology

Organ-restricted vascular delivery of nanoparticles for lung cancer therapy

D. A. Bolukbas, S. Datz, C. Meyer-Schwickerath, C. Morrone, A. Doryab, D. Goessl, M. Vreka, L. Yang, C. Argyo, S. H. van Rijt, M. Lindner, O. Eickelberg, T. Stoeger, O. Schmid, S. Lindstedt, , S. Meiners

This study introduces organ-restricted vascular delivery to enhance nanoparticle targeting to lung tumors, showing improved cellular uptake compared to systemic or intratracheal administration.

bioRxiv · Mar 5, 2020Pharmacology & Toxicology

Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition

R. M. Wasnick, M. Korfei, K. Piskulak, I. Henneke, J. Wilhelm, P. Mahavadi, D. von der Beck, M. Koch, I. Shalashova, O. Klymenko, L. Fink, H. Witt, H. Hackstein, E. El Agha, S. Bellusci, , A. Guenther

Notch1 inhibition restores alveolar epithelial differentiation, reduces surface tension, and reverses matrix deposition in lung fibrosis.

bioRxiv · Mar 23, 2019 · PreprintCell Biology