Bacterial threat assessment of bacteriophage infection is mediated by intracellular polyamine accumulation and Gac/Rsm signaling
C. D. de Mattos, A. Nemudryi, D. Faith, D. C. Bublitz, L. Hammond, M. Kinnersley, C. M. Schwartzkopf, A. J. Robinson, A. Joyce, L. A. Michaels, R. Brzozowski, A. Coluccio, D. Xing, J. Uchiyama, L. K. Jennings, , P. R. Secor
This study shows that Pseudomonas aeruginosa uses intracellular polyamine accumulation and Gac/Rsm signaling to assess bacterial cell death and inhibit phage replication.
bioRxiv · Apr 1, 2022Microbiology