Author

D. Führer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

G. S. Hönes· 3 shared L. C. Moeller· 3 shared D. Geist· 2 shared H. Fuchs· 2 shared J. Mittag· 2 shared K. Lorenz· 2 shared N. Spielmann· 2 shared S. C. Grund· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

G. S. Hönes

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3 papers

Recent·Most cited

Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ

G. S. Hönes, D. Geist, C. Wenzek, P. T. Pfluger, T. D. Müller, O. V. Amarie, L. Becker, N. Dragano, L. Garrett, S. M. Hölter, B. Rathkolb, J. Rozman, N. Spielmann, I. Treise, E. Wolf, , L. C. Moeller

This study compares TRα and TRβ knockout mice with DNA-binding-deficient mutants to show noncanonical TR signaling contributes to physiological functions beyond canonical genomic pathways.

bioRxiv · Nov 26, 2023Physiology

Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice

D. Geist, G. S. Hönes, S. C. Grund, J. Pape, D. Siemes, P. Spangenberg, E. Tolstik, S. Dörr, N. Spielmann, H. Fuchs, V. Gailus-Durner, M. Hrabe de Angelis, J. Mittag, D. R. Engel, D. Führer, , L. C. Moeller

This study shows that thyroid hormone-induced cardiac hypertrophy relies on noncanonical TR action, while heart rate regulation depends on canonical TR action, with TRβ compensating for TR absence.

bioRxiv · Nov 24, 2023Physiology

Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice

H. Kerp, J. Gassen, S. C. Grund, G. S. Hönes, S. Dörr, J. Mittag, N. Härting, F. Kaiser, L. C. Moeller, K. Lorenz, D. Führer

This study shows that thyroid hormone levels do not significantly affect cardiac recovery in old mice with preexisting pressure-induced cardiac damage.

bioRxiv · Nov 17, 2023Physiology