Author

J. Mittag

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 6

Signature Assays, Organisms & Methods

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Organism:mouse· 6 Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:clustering· 1

Frequent Co-Authors

H. Oster· 3 shared L. C. Moeller· 3 shared L. Harder· 3 shared L. V. de Assis· 3 shared D. Führer· 2 shared G. S. Hönes· 2 shared I. Cascorbi· 2 shared I. Nagel· 2 shared

Activity by Year

2022-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPhysiology

H. Oster

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Author profile →

6 papers

Recent·Most cited

Thyroid hormone receptor beta (THRB) dependent regulation of diurnal hepatic lipid metabolism in adult male mice

L. V. de Assis, L. Harder, J. Inderhees, O. Johren, J. Mittag, H. Oster

This study investigates how THRB affects diurnal hepatic lipid metabolism in adult male mice, finding THRB deficiency disrupts metabolic rhythms and promotes steatosis.

bioRxiv · Jan 30, 2024Physiology

Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice

D. Geist, G. S. Hönes, S. C. Grund, J. Pape, D. Siemes, P. Spangenberg, E. Tolstik, S. Dörr, N. Spielmann, H. Fuchs, V. Gailus-Durner, M. Hrabe de Angelis, J. Mittag, D. R. Engel, D. Führer, , L. C. Moeller

This study shows that thyroid hormone-induced cardiac hypertrophy relies on noncanonical TR action, while heart rate regulation depends on canonical TR action, with TRβ compensating for TR absence.

bioRxiv · Nov 24, 2023Physiology

Partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy in mice lacking thyroid hormone receptor beta

R. Dore, S. C. Sentis, K. Johann, N. Lopez-Alcantara, J. Resch, L. C. Moeller, D. Fuehrer, B. Obermayer-Wasserscheid, R. Opitz, J. Mittag

This study shows that TR{beta}-KO mice exhibit partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy when studied at thermoneutrality.

bioRxiv · Nov 21, 2023Physiology

Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice

H. Kerp, J. Gassen, S. C. Grund, G. S. Hönes, S. Dörr, J. Mittag, N. Härting, F. Kaiser, L. C. Moeller, K. Lorenz, D. Führer

This study shows that thyroid hormone levels do not significantly affect cardiac recovery in old mice with preexisting pressure-induced cardiac damage.

bioRxiv · Nov 17, 2023Physiology

Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice

L. V. de Assis, L. Harder, J. T. Lacerda, R. Parsons, M. Kaehler, I. Cascorbi, I. Nagel, O. Rawashdeh, J. Mittag, H. Oster

This study investigates how thyroid hormone levels affect liver circadian transcriptome rhythms in mice, identifying 516 genes as molecular markers of liver TH state.

bioRxiv · Sep 23, 2023Physiology

Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation

L. V. de Assis, L. Harder, J. T. Lacerda, R. Parsons, M. Kaehler, I. Cascorbi, I. Nagel, O. Rawashdeh, J. Mittag, H. Oster

This study shows that T3 supplementation reorganizes liver transcriptome rhythms, affecting metabolic processes independently of local circadian clocks.

bioRxiv · Apr 28, 2022Physiology