Author

B. Rathkolb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 4 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2

Frequent Co-Authors

H. Fuchs· 5 shared J. Calzada-Wack· 4 shared M. Hrabe de Angelis· 4 shared V. Gailus-Durner· 4 shared A. Sanz-Moreno· 3 shared J. Rozman· 3 shared L. Becker· 3 shared R. Gerlini· 3 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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5 shared papersPhysiology

H. Fuchs

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Author profile →

6 papers

Recent·Most cited

eATP/P2X7R axis drives nanoparticle induced neutrophil recruitment in the pulmonary microcirculation

C. Li, Q. Liu, L. Han, R. Immler, B. Rathkolb, J. Secklehner, M. Hrabe de Angelis, A. O. Yildirim, A. Nicke, L. M. Carlin, M. Sperandio, T. Stoeger, M. Rehberg

This study identifies the eATP/P2X7R axis as a driver of nanoparticle-induced neutrophil recruitment in the pulmonary microcirculation using intravital microscopy in mice.

bioRxiv · Mar 11, 2024 · PreprintImmunology

Comparative phenotyping of mice reveals canonical and noncanonical physiological functions of TRα and TRβ

G. S. Hönes, D. Geist, C. Wenzek, P. T. Pfluger, T. D. Müller, O. V. Amarie, L. Becker, N. Dragano, L. Garrett, S. M. Hölter, B. Rathkolb, J. Rozman, N. Spielmann, I. Treise, E. Wolf, , L. C. Moeller

This study compares TRα and TRβ knockout mice with DNA-binding-deficient mutants to show noncanonical TR signaling contributes to physiological functions beyond canonical genomic pathways.

bioRxiv · Nov 26, 2023Physiology

New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance

T. Klein-Rodewald, K. Micklich, A. Sanz-Moreno, M. Tost, J. Calzada-Wack, T. Adler, M. Klaften, S. Sabrautzki, B. Aigner, M. Kraiger, V. Gailus-Durner, H. Fuchs, German Mouse Clinic Consortium, A. Gruender, H. Pahl, , B. Rathkolb

This paper describes a new mouse model with a KIT mutation that develops late-onset mammary tumors with high penetrance and lung metastasis.

bioRxiv · Aug 23, 2022Cancer Biology

Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice

K. Xie, H. Fuchs, E. Scifo, D. Liu, A. Aziz, J. A. Aguilar- Pimentel, O. V. Amarie, L. Becker, P. da Silva-Buttkus, J. Calzada-Wack, Y.-L. Cho, Y. Deng, A. C. Edwards, L. Garrett, C. Georgopoulou, , Schmidt-Weber

This study uses large-scale phenotyping in mice to show that longevity regulators affect age-sensitive phenotypes before detectable aging begins, rather than slowing aging rates.

bioRxiv · Mar 25, 2022Physiology

Insights into energy balance dysregulation from a mouse model of methylmalonic aciduria

M. Lucienne, R. Gerlini, B. Rathkolb, J. Calzada-Wack, P. Forny, S. Wüest, A. Kaech, F. Traversi, M. Forny, C. Bürer, J. A. Aguilar-Pimentel, M. Irmler, J. Beckers, S. Sauer, S. Kölker, , M. Hrabe de Angelis

This study examines a mouse model of methylmalonic aciduria, finding reduced energy expenditure, altered metabolism, and metabolic inflexibility.

bioRxiv · Nov 30, 2021Physiology

Dietary intervention improves health metrics and life expectancy of the genetically obese DU6 (Titan) mouse

A. Mueller-Eigner, A. Sanz-Moreno, I. de-Diego, A. Venkateswaran Venkatasubramani, M. Langhammer, R. Gerlini, B. Rathkolb, A. Aguilar-Pimentel, T. Klein-Rodewald, J. Calzada-Wack, L. Becker, S. Palma-Vera, B. Gille, I. Forne, A. Imhof, , S. Peleg

The study characterizes the Titan mouse as a model for metabolically unhealthy obesity and shows that dietary intervention improves its health and extends lifespan.

bioRxiv · May 11, 2020Physiology