Author

D. Geanon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:cell type annotation· 5 Research Focus:differential expression· 4 Assay:flow cytometry· 4 Research Focus:cell-cell communication· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

B. Lee· 5 shared S. Kim-Schulze· 4 shared A. H. Rahman· 3 shared G. Kelly· 3 shared A. Horowitz· 2 shared A. M. Farkas· 2 shared B. Salome· 2 shared D. D'Souza· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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5 shared papersImmunology

B. Lee

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Author profile →

6 papers

Recent·Most cited

Understanding the heterogeneity of alloreactive natural killer cell function inkidney transplantation

D. F. Ruan, M. Fribourg, Y. Yuki, Y.-H. Park, M. Martin, G. Kelly, B. Lee, R. Lee, R. M. de Real, D. Geanon, S. Kim-Schulze, M. McCarthy, N. Chun, P. Cravedi, M. Carrington, , A. Horowitz

This study identifies NK cell subpopulations and their functional responses in kidney transplant patients, linking pre-transplant NK cell characteristics to long-term graft function.

bioRxiv · Sep 1, 2023 · PreprintImmunology

Elevated HLA-E and NKG2A as a consequence of chronic immune activation defines resistance to M. bovis BCG immunotherapy in Non-Muscle-Invasive Bladder Cancer

D. Ranti, Y.-S. Wang, J. Daza, C. Bieber, B. Salome, E. Merritt, J.-A. Cavallo, E. Hegewisch-Solloa, E. M. Mace, A. M. Farkas, S. Schroff, B. Lee, M. Tran, T. Strandgaard, S. V. Lindskrog, , A. Horowitz

The paper identifies elevated HLA-E and NKG2A as markers of resistance to BCG immunotherapy in NMIBC, linked to immune escape mechanisms.

bioRxiv · Mar 6, 2022 · PreprintImmunology

NKG2A and HLA-E define a novel alternative immune checkpoint axis in bladder cancer

B. Salome, J. P. Sfakianos, J. Daza, A. Charap, C. Hammer, R. Banchereau, A. M. Farkas, D. Geanon, G. Kelly, R. M. de Real, B. Lee, K. G. Beaumont, S. Shroff, Y. S. A. Wang, Y.-C. Wang, , Mariath

This study identifies NKG2A and HLA-E as an alternative immune checkpoint axis in bladder cancer, showing NKG2A+ CD8 T cells can bypass HLA-ABC loss through TCR-independent cytotoxicity.

bioRxiv · Mar 4, 2022 · PreprintImmunology

Shift of lung macrophage composition is associated with COVID-19 disease severity and recovery

S. T. Chen, M. D. Park, D. M. Del Valle, M. Buckup, A. Tabachnikova, N. W. Simons, K. Mouskas, B. Lee, D. Geanon, D. D'Souza, T. Dawson, R. Marvin, K. Nie, R. Thompson, Z. Zhao, , M. Merad

This study identifies shifts in lung macrophage composition linked to COVID-19 severity and recovery, suggesting therapeutic strategies targeting macrophage function.

bioRxiv · Jan 11, 2022 · PreprintImmunology

Multimodal Single-Cell Characterization of the Human Granulocyte Lineage

J. Qi, D. D'Souza, T. Dawson, D. Geanon, H. Stefanos, R. Marvin, L. Walker, A. H. Rahman

This study uses multi-modal CITE-seq to accurately characterize human granulocytes, showing higher transcript detection with BD Rhapsody compared to 10X Genomics.

bioRxiv · Jun 12, 2021 · PreprintImmunology

Donor-Specific Plasma Factors Contribute to Aberrant Staining Artifacts with a Commercial Lyophilized Mass Cytometry Antibody Panel

D. Geanon, B. Lee, A. H. Rahman

The paper identifies donor-specific plasma factors causing aberrant staining in a commercial CyTOF antibody panel and proposes mitigation strategies.

bioRxiv · Nov 30, 2020 · PreprintImmunology