Author

D. Guillotin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Plate· 2 shared A. Blanchard· 1 shared A. Fisher· 1 shared A. Taylor· 1 shared B. Selvarajah· 1 shared G. Contento· 1 shared G. Miele· 1 shared J.-A. A. Wilson· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

M. Plate

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2 papers

Recent·Most cited

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

G. Contento, J.-A. A. Wilson, B. Selvarajah, M. Plate, D. Guillotin, V. Morales, M. Trevisani, V. Pitozzi, K. Bianchi, R. C. Chambers

This study shows that pyruvate metabolism affects fibroblast response to GLS1 inhibition during fibrosis, suggesting combined targeting of pyruvate metabolism and glutaminolysis as a therapeutic strategy.

bioRxiv · Jan 30, 2024Cell Biology

Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis

D. Guillotin, A. Taylor, M. Plate, P. Mercer, L. Edwards, R. Haggart, G. Miele, R. McAnulty, T. Maher, R. E. Hynds, M. Jamal-Hanjani, R. Marshall, A. Fisher, A. Blanchard, R. Chambers

This study identifies key transcriptional pathways in IPF fibroblastic foci using RNA-seq and bioinformatics, highlighting the TSC2/RHEB axis as a potential therapeutic target for fibrosis.

bioRxiv · Mar 10, 2020Cell Biology