Author

D. J. Brogan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

T. Yang· 3 shared I. Antoshechkin· 2 shared M. Li· 2 shared O. Akbari· 2 shared R. Sun· 2 shared A. Buchman· 1 shared A. J. Lopez-Denman· 1 shared C. Montell· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

T. Yang

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Author profile →

3 papers

Recent·Most cited

Targeting Sex Determination to Suppress Mosquito Populations

M. Li, N. P. Kandul, R. Sun, T. Yang, E. D. Benetta, D. J. Brogan, I. Antoshechkin, H. M. Sanchez C., Y. Zhan, N. A. DeBeaubien, Y. M. Loh, M. P. Su, C. Montell, J. M. Marshall, O. S. Akbari

This paper develops a CRISPR-based sterile insect technique to suppress Aedes aegypti populations by generating sterile males that outcompete wild mosquitoes.

bioRxiv · Apr 18, 2023Bioengineering

Engineered Antiviral Sensor Targets Infected Mosquitoes

E. Dalla Benetta, A. J. Lopez-Denman, H.-H. Li, R. A. Masri, D. J. Brogan, M. Bui, T. Yang, M. Li, M. Dunn, M. J. Klein, S. Jackson, K. Catalan, K. R. Blasdell, P. Tng, I. Antoshechkin, , O. Akbari

The paper develops REAPER, a Cas13-based antiviral sensor that kills infected mosquitoes upon activation by arbovirus infection.

bioRxiv · Jan 27, 2023Bioengineering

Programmable RNA Targeting using CasRx in Flies

A. Buchman, D. J. Brogan, R. Sun, T. Yang, P. Hsu, O. Akbari

This study evaluates the use of CasRx, a Cas ribonuclease, for programmable RNA targeting in Drosophila melanogaster, showing transcript targeting, toxicity, and off-target effects.

bioRxiv · Apr 3, 2020Bioengineering