Author

D. J. Conway

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:plant (other)· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

G. A. Awandare· 4 shared L. B. Stewart· 4 shared A. Claessens· 2 shared D. P. Kwiatkowski· 2 shared E. Drury· 2 shared A. Amambua-Ngwa· 1 shared A. Cortes· 1 shared A. D. Ahouidi· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

G. A. Awandare

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Author profile →

5 papers

Recent·Most cited

Genomic variation during culture-adaptation of genetically complex Plasmodium falciparum clinical isolates

A. Claessens, L. B. Stewart, E. Drury, A. D. Ahouidi, A. Amambua-Ngwa, M. Diakite, D. P. Kwiatkowski, G. A. Awandare, D. J. Conway

The paper analyzes genomic variation in Plasmodium falciparum clinical isolates during culture adaptation, finding that some isolates fix to single genotypes while others retain diversity, with loss-of-function mutants emerging in multiple-genotype infections.

bioRxiv · Sep 14, 2022 · PreprintMicrobiology

Variation in Plasmodium falciparum sexual commitment rates and responses to environmental modification

L. B. Stewart, A. Freville, T. S. Voss, D. A. Baker, G. A. Awandare, D. J. Conway

This study measures sexual commitment rates in Plasmodium falciparum using two methods, finds higher sensitivity with an early marker, and reports variation across isolates and lab lines.

bioRxiv · Feb 14, 2022 · PreprintMicrobiology

The PfAP2-HS transcription factor protects malaria parasites from febrile temperatures

E. Tinto-Font, L. Michel-Todo, T. J. Russell, N. Casas-Vila, D. J. Conway, Z. Bozdech, M. Llinas, A. Cortes

This study identifies PfAP2-HS as a transcription factor that enables malaria parasites to survive febrile temperatures by activating chaperone genes.

bioRxiv · Mar 15, 2021Microbiology

Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites

L. B. Stewart, O. Diez-Ingelmo, A. Claessens, J. Abugri, R. Pearson, S. Goncalves, E. Drury, D. P. Kwiatkowski, G. A. Awandare, D. J. Conway

The paper shows that variation in the multiplication rate of Plasmodium falciparum correlates with infection intensity and virulence in human malaria.

Communications Biology · Oct 28, 2020Peer-reviewedMicrobiology

Plasmodium falciparum schizont stage transcriptome variation among clinical isolates and laboratory-adapted clones

S. J. Tarr, O. Diaz-Ingelmo, L. B. Stewart, S. E. Hocking, L. Murray, C. W. Duffy, T. D. Otto, L. Chappell, J. C. Rayner, G. A. Awandare, D. J. Conway

The paper analyzes transcriptome variation in Plasmodium falciparum schizonts across clinical isolates and lab-adapted clones using RNA-seq, identifying genes with differential expression and validating findings with RT-qPCR.

bioRxiv · Jun 22, 2018Cell Biology