Author

D. K. W. Chu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

J. S. M. Peiris· 2 shared L. L. M. Poon· 2 shared A. Aliy· 1 shared A. Muluneh· 1 shared C. K.-P. Mok· 1 shared D. S. Lobago· 1 shared D. Zewde· 1 shared E. Walelign· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

J. S. M. Peiris

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutation nsp6 L232F associated with MERS-CoV zoonotic transmission confers higher viral replication in human respiratory tract cultures ex-vivo

R. T. So, D. K. W. Chu, K. P. Y. Hui, C. K.-P. Mok, S. Sanyal, J. M. Nicholls, J. C. W. Ho, M. C. Cheung, K. C. NG, H. W. Yeung, M. C. W. Chan, L. L. M. Poon, J. Zhao, J. S. M. Peiris

This study identifies the nsp6 L232F mutation in MERS-CoV as enhancing viral replication in human respiratory tissues and mice, suggesting a role in human adaptation.

bioRxiv · Mar 27, 2023Microbiology

Cross Sectional Study Of Middle East Respiratory Syndrome (MERS-CoV Infection) In Camels At Selected Sites Of Amibara District, Afar Region, Ethiopia

D. S. Lobago, G. Mamo, F. Aklilu, D. Zewde, E. Walelign, A. Muluneh, A. Aliy, T. Mirkena, N. Tewolde, G. Gari, G. van't Klooster, I. Elmasry, S. VonDobschuetz, J. S. M. S. Peiris, D. K. W. Chu, , Y. Jobire

This study found high MERS-CoV seroprevalence in camels but no active viral RNA, suggesting the need for further research on viral circulation and transmission.

bioRxiv · Oct 25, 2020 · PreprintMicrobiology

Multivariate Analyses of Codon Usage of SARS-CoV-2 and other betacoronaviruses

H. Gu, D. K. W. Chu, J. S. M. Peiris, L. L. M. Poon

This study analyzes codon usage patterns of SARS-CoV-2 and betacoronaviruses using multivariate methods, finding similar amino acid usage to bat and human SARSr-CoVs but distinct synonymous codon usage in spike and membrane genes.

bioRxiv · Feb 15, 2020Evolutionary Biology