Author

D. Reddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

S. Bhattacharya· 2 shared F. Li· 1 shared H. Li· 1 shared J. Workman· 1 shared L. Florens· 1 shared M. Rashid· 1 shared M. Washburn· 1 shared N. Zhang· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

S. Bhattacharya

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2 papers

Recent·Most cited

Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing

S. Bhattacharya, S. Wang, D. Reddy, S. Shen, Y. Zhang, N. Zhang, H. Li, M. Washburn, L. Florens, Y. Shi, F. Li, J. Workman

This study reveals the structural basis of SETD2 methyltransferase interaction with hnRNP L paralogs, showing how a leucine pair in SETD2 interacts with hnRNP L RRM2 and affects splicing regulation.

bioRxiv · May 22, 2021Biochemistry

DNA methylation mediated downregulation of histone H3 variant H3.3 affects cell proliferation contributing to the development of HCC

S. Gupta, D. Reddy, S. Bhattacharya, S. Shah, M. Rashid

The paper shows that DNA methylation reduces H3.3 levels in HCC, affecting transcription and cell proliferation, and suggests DNMT and HDAC inhibitors as potential therapies.

bioRxiv · May 23, 2020Cancer Biology