M. Rashid

Combinatorial cooperativity can facilitate epithelial-mesenchymal transition in a miR200-Zeb feedback network

This study shows that combinatorial cooperativity in the miR200-Zeb feedback network enables epithelial-mesenchymal transition and hybrid phenotypes in carcinoma cells.

RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson's Disease

The paper uses single-nucleus RNA- and ATAC-sequencing to identify a CD83+ microglial subpopulation depleted in Parkinson's disease, with implications for neuronal vulnerability.

Differential expression of H2A isoforms contribute to tissue and lineage specificity with HIST2H2AC as a potential cancer biomarker

The paper investigates H2A isoform expression across normal tissues and tumors, finding tissue-specific patterns and cancer-specific overexpression of HIST2H2AC.

Surveillance of genetic diversity and evolution in locally transmitted SARS-CoV-2 in Pakistan during the first wave of the COVID-19 pandemic

The paper tracks genetic mutations and lineage evolution of SARS-CoV-2 in Pakistan during the first pandemic wave using whole genome sequencing of 48 samples.

Unfolding the Apoptotic Mechanism of Antioxidant Enriched-Leaves of Tabebuia pallida in EAC Cells

This study investigates the apoptotic effects of Tabebuia pallida extracts on EAC cells using cytotoxicity assays, gene expression analysis, and compound identification.

Facial expressions of emotional stress in horses

This study identifies facial expressions in stressed horses using video recordings and a machine-learning classifier, finding significant correlations between specific facial traits and stress.

Association of poor virus specific immunoglobulin G antibodyresponses with higher viral load is seen in Bangladeshi pregnantwomen having acute Hepatitis E Genotype 1 infection

This study finds that Bangladeshi pregnant women with acute Hepatitis E Genotype 1 infection have lower IgG antibody responses and higher viral loads compared to non-pregnant women with the same infection.

DNA methylation mediated downregulation of histone H3 variant H3.3 affects cell proliferation contributing to the development of HCC

The paper shows that DNA methylation reduces H3.3 levels in HCC, affecting transcription and cell proliferation, and suggests DNMT and HDAC inhibitors as potential therapies.

Equine Facial Action Coding System for determination of pain-related facial responses in videos of horses

The paper develops and validates an Equine Facial Action Coding System (EquiFACS) to identify pain-related facial expressions in horses using video analysis.