Author

D. Rifat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:whole-genome sequencing· 2

Frequent Co-Authors

S.-Y. Li· 3 shared E. Nuermberger· 2 shared G. Bashiri· 2 shared J. Lee· 2 shared J.-P. Lanoix· 2 shared B. N. Kreiswirth· 1 shared E. L. Nuermberger· 1 shared J. C. Sacchettini· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

S.-Y. Li

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3 papers

Recent·Most cited

In vitro and in vivo validation of cwlM and pbpB essentiality for viability and resistance to imipenem in Mycobacterium abscessus

E. L. Nuermberger, J. I. Lee, S.-Y. Li, D. Rifat, N. Kurepina, L. Chen, B. N. Kreiswirth

This study validates cwlM and pbpB as essential genes for Mycobacterium abscessus viability and imipenem resistance using CRISPRi in vitro and in vivo.

bioRxiv · Mar 8, 2024 · PreprintMicrobiology

Mutations in fbiD(Rv2983) as a novel determinant of resistance to pretomanid and delamanid in Mycobacterium tuberculosis

D. Rifat, S.-Y. Li, T. R. Ioerger, K. Shah, J.-P. Lanoix, J. Lee, G. Bashiri, J. C. Sacchettini, E. Nuermberger

This study identifies mutations in fbiD(Rv2983) as a novel determinant of resistance to pretomanid and delamanid in Mycobacterium tuberculosis through in vitro and in vivo experiments.

bioRxiv · Sep 10, 2020Microbiology

Mutations in Rv2983 as a novel determinant of resistance to nitroimidazole drugs in Mycobacterium tuberculosis

D. Rifat, S.-Y. Li, T. Ioerger, J.-P. Lanoix, J. Lee, G. Bashiri, J. Sacchettini, E. Nuermberger

This paper identifies Rv2983 as a novel gene conferring resistance to nitroimidazole drugs in Mycobacterium tuberculosis and highlights the challenges in detecting such resistance.

bioRxiv · Oct 31, 2018 · PreprintMicrobiology