Author

D. Segara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Swarbrick· 3 shared E. Lim· 3 shared A. Parker· 2 shared A. S. Cazet· 2 shared C. Mak· 2 shared C.-L. Chan· 2 shared D. L. Roden· 2 shared G. Al-Eryani· 2 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Swarbrick

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Author profile →

3 papers

Recent·Most cited

MDM2 Inhibition in Combination with Endocrine Therapy and CDK4/6 Inhibition for the Treatment of ER-Positive Breast Cancer.

N. Portman, H. H. Milioli, S. Alexandrou, R. Coulson, A. Yong, K. J. Fernandez, K. Chia, D. Segara, A. Parker, S. Haupt, Y. Haupt, W. D. Tilley, A. Swarbrick, C. E. Caldon, E. Lim

This study evaluates MDM2 inhibition combined with endocrine therapy and CDK4/6 inhibition in ER-positive breast cancer, showing synergistic anti-tumor effects in resistant models.

bioRxiv · Jun 9, 2020Cancer Biology

Single-cell analysis reveals diverse stromal subsets associated with immune evasion in triple-negative breast cancer

S. Z. Wu, D. L. Roden, C. Wang, H. Holliday, K. Harvey, A. S. Cazet, K. J. Murphy, B. Pereira, G. Al-Eryani, N. Bartonicek, R. Hou, J. R. Torpy, S. Junankar, C.-L. Chan, E. Lam, , A. Swarbrick

This study identifies diverse stromal subsets in TNBC using single-cell RNA-seq and links them to immune evasion mechanisms and therapeutic targets.

bioRxiv · Jun 4, 2020Cancer Biology

Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis

S. Z. Wu, D. L. Roden, G. Al-Eryani, N. Bartonicek, K. Harvey, A. S. Cazet, C.-L. Chan, S. Junankar, M. N. Hui, E. Millar, J. Beretov, L. Horvath, A. M. Joshua, P. Stricker, J. S. Wilmott, , A. Swarbrick

This study shows that cryopreservation of human cancers preserves tumour heterogeneity for single-cell multi-omics analysis, with comparable results to fresh tissue.

bioRxiv · Jun 4, 2020Cancer Biology