Author

D. Tao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:C. elegans· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. A. LeClair· 2 shared D. Xie· 2 shared J. Shen· 2 shared L. Liu· 2 shared Q. Huang· 2 shared S. Feng· 2 shared W. Jia· 2 shared X. Li· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

C. A. LeClair

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Author profile →

6 papers

Recent·Most cited

Pleistocene glaciation advances the younger temporal dimension of species diversification in a major biodiversity hotspot

S. K. Rana, H. K. Rana, J. B. Landis, T. Kuang, J. Chen, H. Wang, D. Tao, C. C. Davis, H. Sun

The paper uses genomic and eco-morphological analysis to reveal recent diversification in the Stellera chamaejasme L. complex, driven by Pleistocene glaciation and biotic factors.

bioRxiv · Aug 10, 2023 · PreprintEvolutionary Biology

An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics

S. G. Borhani, M. Z. Levine, L. H. Krumpe, J. Wilson, C. Hendrich, B. O'Keefe, D. Lo, G. Sittampalam, A. Godfrey, R. D. Lunsford, V. Mangalampalli, D. Tao, C. A. LeClair, A. Thole, D. Frey, , G. Rao

This paper describes a cell-free biomanufacturing approach for rapid production of griffithsin, a broad-spectrum antiviral protein, demonstrating its efficacy against SARS-CoV-2 and HIV-1.

bioRxiv · Dec 19, 2022Bioengineering

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology

J. Inglese, P. Dranchak, E. Oliphant, B. Queme, L. Lamy, Y. Wang, R. Huang, M. Xia, D. Tao

This paper describes an in vivo qHTS method using C. elegans to assess drug toxicity and therapeutic potential, demonstrating its feasibility with anti-infective agents and toxicological compounds.

bioRxiv · Aug 26, 2022Pharmacology & Toxicology

DAB2IP inhibits p53 ubiquitin-mediated degradation by competitively binding to GRP75 and suppresses tumor malignancy in colon cancer

J. Shen, S. Feng, J. Deng, Q. Huang, D. Zhao, W. Jia, X. Li, D. Tao, J. Gong, D. Xie, L. Liu

This study identifies DAB2IP as a tumor suppressor in colon cancer that inhibits p53 degradation by competing with GRP75 for binding, thereby enhancing p53 stability and suppressing tumor growth.

bioRxiv · Jun 28, 2021 · PreprintCancer Biology

YAP1 induces invadopodia formation by transcriptionally activating TIAM1 through its enhancer in breast cancer

J. Shen, Q. Huang, S. Feng, W. Jia, L. Liu, X. Li, D. Tao, D. Xie

This study shows YAP1 promotes breast cancer metastasis by enhancing TIAM1 expression through its enhancer, leading to increased RAC1 activity and invadopodia formation.

bioRxiv · Mar 2, 2021Cancer Biology

A Versatile Polypharmacology Platform Promotes Cytoprotection and Viability of Human Pluripotent and Differentiated Cells

Y. Chen, C. A. Tristan, L. Chen, V. Jovanovic, C. Malley, P.-H. Chu, S. Ryu, T. Deng, P. Ormanoglu, D. Tao, Y. Fang, J. Slamecka, C. A. LeClair, S. Michael, C. P. Austin, , I. Singec

The paper identifies a small molecule cocktail, CEPT, that enhances the viability and cytoprotection of human pluripotent and differentiated cells through multi-target drug combinations.

bioRxiv · Oct 22, 2019Cell Biology