A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding and cytopathogenicity
I. Manuelyan, A. M. Schmoker, B. L. Yount, P. Eisenhauer, J. I. Keller, C. Gold, D. Terino, C. M. Ziegler, J. Alexander, H. E. Driscoll, E. Hutchinson, D. Bhella, C. D. Syme, D. G. Widman, M. T. Heise, , J. W. Botten
This study maps host-driven post-translational modifications on the Zika virus proteome, identifies key phosphosites, and shows how an FDA-approved kinase inhibitor blocks viral growth.
bioRxiv · Nov 24, 2021 · PreprintMicrobiology