E. Hutchinson

Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome

The paper identifies cryptic proteins from deletion-containing viral genomes that inhibit influenza virus replication and expand its proteome.

Backscattering Mueller Matrix polarimetry on whole brain specimens shows promise for minimally invasive mapping of microstructural orientation features

This study uses backscattering Mueller Matrix polarimetry to map microstructural orientation features in whole brain specimens, showing promise for validating dMRI results in both gray and white matter.

Zoonotic avian influenza viruses evade human BTN3A3 restriction

This study identifies BTN3A3 as a human restriction factor that inhibits avian influenza viruses but not human IAVs, with resistance linked to specific NP mutations.

Superinfection exclusion creates spatially distinct influenza virus populations

This study shows that superinfection exclusion (SIE) creates spatially distinct influenza virus populations, limiting genome interactions between virus subpopulations as they spread within host tissues.

A global map of the Zika virus phosphoproteome reveals host-driven regulation of viral budding and cytopathogenicity

This study maps host-driven post-translational modifications on the Zika virus proteome, identifies key phosphosites, and shows how an FDA-approved kinase inhibitor blocks viral growth.

Single-particle measurements of filamentous influenza virions reveal damage induced by freezing

The paper investigates damage to influenza virus filaments caused by freezing and recommends mitigation strategies to improve functional studies.

Constitutive TRIM22 expression within the respiratory tract identifies tissue-specific and cell-type dependent intrinsic immune barriers to influenza A virus infection

This study identifies TRIM22 as a constitutively expressed antiviral factor in the respiratory tract that restricts influenza A virus infection independently of cytokine-mediated immunity.