Author

D. W. Nowakowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

K. M. Ori-McKenney· 3 shared R. J. McKenney· 3 shared S. Simo· 2 shared A. Gennerich· 1 shared A. J. Lam· 1 shared A. Lam· 1 shared A. M. Downing· 1 shared A. Ramkumar· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiophysics

K. M. Ori-McKenney

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Highly Conserved 310-Helix Within the Kinesin Motor Domain is Critical for Kinesin Function and Human Health.

A. J. Lam, L. Rao, Y. Anazawa, K. Okada, K. Chiba, S. Niwa, A. Gennerich, D. W. Nowakowski, R. J. McKenney

This study identifies a conserved 310-helix in KIF1A critical for motor function and human health, showing that the P305L mutation disrupts microtubule association and motor performance.

bioRxiv · Sep 22, 2020Biophysics

Autoregulatory control of microtubule binding in the oncogene, doublecortin-like kinase 1

M. M. Rogers, A. Ramkumar, A. M. Downing, H. Bodin, J. Castro, D. W. Nowakowski, K. M. Ori-McKenney

This study identifies autophosphorylation as a mechanism regulating DCLK1 kinase activity and microtubule binding affinity, offering insights into its role in cancer.

bioRxiv · Jun 12, 2020 · PreprintBiochemistry

A Combinatorial MAP Code Dictates Polarized Microtubule Transport

B. Y. Monroy, T. C. Tan, J. M. Oclaman, J. S. Han, S. Simo, D. W. Nowakowski, R. J. McKenney, K. M. Ori-McKenney

This study shows that combinations of microtubule-associated proteins (MAPs) influence motor-cargo transport directionality, suggesting a combinatorial MAP code that biases microtubule movement.

bioRxiv · Aug 10, 2019Biophysics

Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions

R. Tan, A. Lam, T. Tan, J. Han, D. W. Nowakowski, M. Vershinin, S. Simo, K. M. Ori-McKenney, R. J. McKenney

The paper shows microtubules regulate tau condensation, which spatially controls microtubule severing enzymes and motor movement.

bioRxiv · Sep 22, 2018Biophysics