Author

Daisuke Tone

RIKEN Center for Biosystems Dynamics Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:statistical model· 1

Frequent Co-Authors

Hiroki R. UedaiD· 3 shared Hiroshi FujishimaiD· 3 shared Hiroshi KiyonariiD· 3 shared Kenta SumiyamaiD· 3 shared Koji L. OdeiD· 3 shared Mari KanekoiD· 3 shared Rikuhiro G. YamadaiD· 3 shared Shoi ShiiD· 3 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Hiroki R. UedaORCID

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Author profile →

3 papers

Recent·Most cited

Post-synaptic competition between calcineurin and PKA regulates mammalian sleep-wake cycles

Yimeng Wang, Siyu Cao, Daisuke Tone, Hiroshi Fujishima, Rikuhiro G. Yamada, Rei-ichiro Ohno, Shoi Shi, Kyoko Matsuzawa, Saori Yada, Mari Kaneko, Hirokazu Sakamoto, Taichi Onishi, Maki Ukai‐Tadenuma, Hideki Ukai, Carina Hanashima, , Hiroki R. Ueda

The paper identifies PKA and phosphatases as regulators of sleep-wake cycles through genetic and functional studies in mice.

Nature · Nov 6, 2024Peer-reviewedNeuroscience

Cortical parvalbumin neurons are responsible for homeostatic sleep rebound through CaMKII activation

Kazuhiro Kon, Koji L. Ode, Tomoyuki Mano, Hiroshi Fujishima, Riina R. Takahashi, Daisuke Tone, Chika Shimizu, Shinnosuke Shiono, Saori Yada, Kyoko Matsuzawa, Shota Y. Yoshida, Junko Yoshida Garçon, Mari Kaneko, Yuta Shinohara, Rikuhiro G. Yamada, , Hiroki R. Ueda

This study identifies CaMKII-dependent activity of cortical parvalbumin neurons as essential for homeostatic sleep rebound following prolonged wakefulness.

Nature Communications · Jul 18, 2024Peer-reviewedNeuroscience

Realization of phosphorylation hypothesis of sleep by mammalian CaMKIIβ

Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, Rei-ichiro Ohno, Maki Ukai‐Tadenuma, Junko Yoshida Garçon, Mari Kaneko, Shoi Shi, , Hiroki R. Ueda

This study shows that CaMKIIβ phosphorylation regulates sleep duration and steps in mammals by modulating kinase activity in excitatory neurons.

bioRxiv · Oct 11, 2021 · PreprintNeuroscience