Rikuhiro G. Yamada

The paper identifies PKA and phosphatases as regulators of sleep-wake cycles through genetic and functional studies in mice.

The paper uses computational models to explore synaptic dynamics during the sleep-wake cycle, finding that wake-like firing patterns decrease synaptic weights while sleep-like patterns increase them, offering a unified framework for synaptic homeodynamics.

This study identifies CaMKII-dependent activity of cortical parvalbumin neurons as essential for homeostatic sleep rebound following prolonged wakefulness.

This study shows that CaMKIIβ phosphorylation regulates sleep duration and steps in mammals by modulating kinase activity in excitatory neurons.

CUBIC-Cloud is a cloud-based framework for analyzing and integrating whole mouse brain data, demonstrating applications in cell distribution, plaque quantification, neuronal activity, and connectivity mapping.