Author

Dan Martinez

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Amber K. WeineriD· 1 shared Andrew J. RechiD· 1 shared Anjali DhalliD· 1 shared Anna EichingeriD· 1 shared Arnulfo MendozaiD· 1 shared Arta SeyedianiD· 1 shared Boris ReizisiD· 1 shared Brigitte C. WidemanniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Amber K. WeinerORCID

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2 papers

Recent·Most cited

Spatial and Single Cell Mapping of Castleman Disease Reveals Key Stromal Cell Types and Cytokine Pathways

David Glenn Smith, Anna Eichinger, Éanna Fennell, Zijun Yidan Xu-Monette, Andrew J. Rech, Julia Wang, Eduardo Esteva, Arta Seyedian, Xiaoxu Yang, Mei Zhang, Dan Martinez, Kai Tan, Minjie Luo, Katherine J. Young, Paul Gerard Murray, , Vinodh Pillai

This study maps the spatial and single-cell landscape of Castleman Disease, identifying key stromal cell types and cytokine pathways involved in disease pathology.

Nature Communications · Jul 1, 2025Peer-reviewedPathology

Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

Nai-Yun Sun, Suresh Kumar, Yoo Sun Kim, Diana Grace Varghese, Arnulfo Mendoza, Rosa Nguyen, Reona Okada, Karlyne M. Reilly, Brigitte C. Widemann, Yves G. Pommier, Fathi Elloumi, Anjali Dhall, Daiki Taniyama, Mayank Patel, Etan R. Aber, , Nitin Roper

This paper identifies DLK1 as a novel immunotherapeutic target in adrenocortical carcinoma, showing it regulates tumor cell plasticity and chemoresistance, and demonstrates the efficacy of a DLK1-targeting antibody-drug conjugate.

Nature Communications · Jul 1, 2025Peer-reviewedCancer Biology