Author

Daniel J. Flood

Rush University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Artemis IatrouiD· 3 shared Chris GaiteriiD· 3 shared Jishu XuiD· 3 shared Nicola A. KearnsiD· 3 shared Sashini L De Tissera· 3 shared David A. Bennett· 2 shared Denis R. AveyiD· 2 shared Himanshu VyasiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Artemis IatrouORCID

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Author profile →

3 papers

Recent·Most cited

Uncovering Plaque-Glia Niches in Human Alzheimer's Disease Brains Using Spatial Transcriptomics

Denis R. Avey, Bernard Ng, Ricardo A. Vialle, Nicola A. Kearns, Kátia de Paiva Lopes, Artemis Iatrou, Sashini L De Tissera, Himanshu Vyas, Devin M. Saunders, Daniel J. Flood, Jishu Xu, Shinya Tasaki, Chris Gaiteri, David A. Bennett, Yanling Wang

The paper uses spatial transcriptomics to analyze Aβ plaques and glial interactions in AD brains, finding that low Aβ areas show more neuronal loss and high-glia areas show inflammation and neurodegeneration.

Molecular Neurodegeneration Advances · Jul 16, 2025Peer-reviewedGenomics

The YTHDF proteins shape the brain gene signatures of Alzheimer's disease

Shinya Tasaki, Denis R. Avey, Nicola A. Kearns, Chunjiang Yu, Sashini L De Tissera, Himanshu Vyas, Lin Cheng, Jishu Xu, Artemis Iatrou, Daniel J. Flood, Wenlong Li, Lisa Laverne Barnes, Katherine L. Rothamel, Aliza P. Wingo, Thomas S. Wingo, , Yanling Wang

This study identifies YTHDF proteins as key regulators of Alzheimer's disease brain gene signatures through m6A-dependent and independent mechanisms.

bioRxiv · Oct 23, 2024 · PreprintNeuroscience

Dissecting the Human Leptomeninges at single-cell resolution

Nicola A. Kearns, Artemis Iatrou, Daniel J. Flood, Sashini L De Tissera, Zachary M. Mullaney, Jishu Xu, Chris Gaiteri, David Alan Bennett, Yanling Wang

This study provides the first single-nuclei profiling of human leptomeninges, identifying cell types and gene expression patterns linked to Alzheimer's disease.

Nature Communications · Nov 3, 2023Peer-reviewedGenomics