Author
Rush University Medical Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Tristan J Philippe, Denis R. Avey, Nicola A. Kearns…·Yanling Wang
This study creates a multi-omic atlas of the choroid plexus in Alzheimer's disease, identifying disease-associated cell state transitions and functional impairments.
Devin Saunders, Faraz A. Sultan, Ricardo A. Vialle…·Yanling Wang
The paper evaluates the AICS-0090 dCas9-KRAB iPSC line for modeling microglia-like cells and their responses to disease-relevant stimuli, finding stimulus-specific transcriptomic and functional responses.
Denis R. Avey, Bernard Ng, Ricardo A. Vialle…·Yanling Wang
The paper uses spatial transcriptomics to analyze Aβ plaques and glial interactions in AD brains, finding that low Aβ areas show more neuronal loss and high-glia areas show inflammation and neurodegeneration.
Bernard Ng, Denis R. Avey, Faraz Sultan…·Yanling Wang
The paper identifies AD-associated lncRNAs with spatial and cell-type-specific expression patterns and shows OIP5-AS1 contributes to microglial activation in AD.
Shinya Tasaki, Denis R. Avey, Nicola A. Kearns…·Yanling Wang
This study identifies YTHDF proteins as key regulators of Alzheimer's disease brain gene signatures through m6A-dependent and independent mechanisms.
Nicola A. Kearns, Artemis Iatrou, Daniel J. Flood…·Yanling Wang
This study provides the first single-nuclei profiling of human leptomeninges, identifying cell types and gene expression patterns linked to Alzheimer's disease.