Artemis Iatrou

This study identifies a unified brain circuit associated with status epilepticus using multimodal lesion mapping and gene expression analysis, showing high accuracy in distinguishing SE from other lesion etiologies.

The paper creates a miRNA atlas of the human prefrontal cortex across aging, identifying age-related miRNA changes and highlighting miR-34a-5p as a key upregulated miRNA in older individuals.

This study maps molecular and genetic signatures of schizophrenia in human prefrontal cortex across spatial scales, revealing altered BDNF-TrkB signaling and inhibitory circuit dysfunction.

The paper performs spatial transcriptomics on the human prefrontal cortex across the lifespan to identify aging-related changes in different cortical layers.

The paper uses spatial transcriptomics to analyze Aβ plaques and glial interactions in AD brains, finding that low Aβ areas show more neuronal loss and high-glia areas show inflammation and neurodegeneration.

The paper identifies AD-associated lncRNAs with spatial and cell-type-specific expression patterns and shows OIP5-AS1 contributes to microglial activation in AD.

This study identifies YTHDF proteins as key regulators of Alzheimer's disease brain gene signatures through m6A-dependent and independent mechanisms.

The paper identifies 46,802 enhancers and 164 psychiatric disorder variants with regulatory effects in the developing cortex and organoids using massively parallel reporter assays and deep learning.

The paper generates a molecular neuroanatomical map of the human prefrontal cortex using spatial transcriptomics and single nucleus RNA-sequencing, revealing novel spatial domains and cell-cell interactions linked to psychiatric disorders.

This study provides the first single-nuclei profiling of human leptomeninges, identifying cell types and gene expression patterns linked to Alzheimer's disease.

This study identifies cell-type-specific epigenetic changes in TNXB in Alzheimer's disease using bulk and single-cell analyses of the dorsal raphe nucleus.