Author
Rush University Medical CenterORCID 0000-0001-8080-8437Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Tristan J Philippe, Denis R. Avey, Nicola A. Kearns…·Yanling Wang
This study creates a multi-omic atlas of the choroid plexus in Alzheimer's disease, identifying disease-associated cell state transitions and functional impairments.
Devin Saunders, Faraz A. Sultan, Ricardo A. Vialle…·Yanling Wang
The paper evaluates the AICS-0090 dCas9-KRAB iPSC line for modeling microglia-like cells and their responses to disease-relevant stimuli, finding stimulus-specific transcriptomic and functional responses.
Denis R. Avey, Bernard Ng, Ricardo A. Vialle…·Yanling Wang
The paper uses spatial transcriptomics to analyze Aβ plaques and glial interactions in AD brains, finding that low Aβ areas show more neuronal loss and high-glia areas show inflammation and neurodegeneration.
Bernard Ng, Denis R. Avey, Faraz Sultan…·Yanling Wang
The paper identifies AD-associated lncRNAs with spatial and cell-type-specific expression patterns and shows OIP5-AS1 contributes to microglial activation in AD.
Shinya Tasaki, Denis R. Avey, Nicola A. Kearns…·Yanling Wang
This study identifies YTHDF proteins as key regulators of Alzheimer's disease brain gene signatures through m6A-dependent and independent mechanisms.