Large-scale Phenotypic Drug Screen Identifies Neuroprotectants in Zebrafish and Mouse Models of Retinitis Pigmentosa
Liyun Zhang, Conan Y. Chen, Jie Fu, Brendan N. Lilley, Cynthia A. Berlinicke, Baranda S. Hansen, Ding Ding, Guohua Wang, Tao Wang, Daniel Shou, Ying Ye, Timothy S. Mulligan, Kevin Emmerich, Meera T. Saxena, Kelsi R. Hall, , Jeff S. Mumm
The paper identifies neuroprotective compounds for retinitis pigmentosa using cross-species drug screens in zebrafish and mouse models, finding additive effects in some combinations.
eLife · Jun 29, 2021Peer-reviewedNeuroscience