Author

Meera T. Saxena

Johns Hopkins UniversityORCID 0000-0002-4060-4218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:zebrafish· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeff S. MummiD· 4 shared David T. White· 3 shared Jiang X. QianiD· 3 shared Kevin EmmerichiD· 3 shared Abigail V. SharrockiD· 2 shared Anneliese CeiseliD· 2 shared David F. AckerleyiD· 2 shared Gianna Graziano· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Jeff S. MummORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 20, 2023

Molecular regulation of retinal regeneration is context specific

Kevin Emmerich, John Hageter, Thanh V. Hoang…·Jeff S. Mumm

The paper identifies 18 genes regulating retinal ganglion cell regeneration in zebrafish using a combination of genetic models and single-cell omics.

3 citations

zebrafishscRNA-seq

𝕏 PostBluesky

NeurosciencePLoS GeneticsPeer-reviewedOct 11, 2023

Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses

Kevin Emmerich, Steven L. Walker, Guohua Wang…·Jeff S. Mumm

The paper compares transcriptomic responses in zebrafish following rod photoreceptor or bipolar cell loss, identifying cell-specific and shared regenerative gene programs and immune-related regulators.

8 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedJun 29, 2021

Large-scale Phenotypic Drug Screen Identifies Neuroprotectants in Zebrafish and Mouse Models of Retinitis Pigmentosa

Liyun Zhang, Conan Y. Chen, Jie Fu…·Jeff S. Mumm

The paper identifies neuroprotective compounds for retinitis pigmentosa using cross-species drug screens in zebrafish and mouse models, finding additive effects in some combinations.

31 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 5, 2020

Dendrimer-targeted immunosuppression of microglia reactivity super-accelerates photoreceptor regeneration in the zebrafish retina

Kevin B. Emmerich, David T. White, Siva P. Kambhampati…·Jeff S. Mumm

This study shows that dendrimer-targeted immunosuppression of microglia accelerates photoreceptor regeneration in zebrafish retinas.

4 citations

zebrafishexperimental assay

𝕏 PostBluesky