Depth-Dependent Alterations in Cerebral Blood and Tissue Oxygenation Associated with Tau in Alzheimer's Disease Models
Nancy E. Ruiz‐Uribe, Mohammed Ali H. Alfadhel, Nina Wolf, Sophia E Murray, Elaina Gross, Ava Devine, Danielle G Shaby, Simin Belali, Sergei A. Vinogradov, Theodore J. Zwang, Martin Thunemann, Sava Sakadžić, Rachel E. Bennett
This study examines depth-dependent changes in cerebral oxygenation in Alzheimer's disease models, finding that tau disrupts oxygen levels and that neuronal loss is not due to local hypoxia.
bioRxiv · Oct 16, 2026 · PreprintNeuroscience