Author

David Georges Salthouse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Zhen WangiD· 3 shared Adeline Feri· 2 shared Amirhossein TaghaviiD· 2 shared Matthew David DisneyiD· 2 shared Álvaro Simba-LahuasiiD· 1 shared Andréas LefevreiD· 1 shared Charles P. AndréiD· 1 shared David BensimoniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBioinformatics

Zhen WangORCID

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Author profile →

3 papers

Recent·Most cited

A chemoinformatics-guided platform for efficient discovery of RNA-binding small molecules: Proof-of-concept for myotonic dystrophy type 1

Amirhossein Taghavi, Jingsong Shan, Xiyuan Yao, Patrick R. A. Zanon, Kisu Sung, Álvaro Simba-Lahuasi, Sylwia Gorlach, Henning Labuhn, David Georges Salthouse, Zhen Wang, Adeline Feri, Matthew David Disney

The paper develops a chemoinformatics platform to discover RNA-binding small molecules, identifying ligands for the r(CUG)exp RNA in DM1 with splicing rescue activity.

bioRxiv · May 13, 2026 · PreprintBioinformatics

NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansion

Amirhossein Taghavi, Jonathan L. Chen, Zhen Wang, Krishshanthi Sinnadurai, David Georges Salthouse, Matthew Ozon, Adeline Feri, Matthew A. Fountain, Shruti Choudhary, Jessica L. Childs‐Disney, Matthew David Disney

This paper reports NMR structures and magnetic force spectroscopy studies of small molecules binding to RNA CAG repeat expansions, revealing their binding modes and structural effects.

bioRxiv · Aug 20, 2024 · PreprintBiophysics

Detecting genetic variation and base modifications together in the same single molecules of DNA and RNA at base pair resolution using a magnetic tweezer platform.

Zhen Wang, Jérôme Maluenda, Laurène Giraut, Thibault Vieille, Andréas Lefevre, David Georges Salthouse, Gaël Radou, Rémi Moulinas, Sandra Astete-Morales, Pol D’Avezac, Geoff Smith, Charles P. André, Jean‐François Allemand, David Bensimon, Vincent Croquette, , Gordon Hamilton

bioRxiv · Apr 3, 2020 · PreprintGenomics