Shruti Choudhary

This paper develops a fluorogenic substrate for Chikungunya virus protease (nsP2) that improves signal-to-noise ratio and specificity for inhibitor screening.

The paper investigates evolved and plastic gene expression differences in adaptation to a novel niche using peacock flies, finding ecotype-specific gene expression changes and an inversion linked to differential expression.

This paper reports NMR structures and magnetic force spectroscopy studies of small molecules binding to RNA CAG repeat expansions, revealing their binding modes and structural effects.

The paper reports NMR structures of small molecules bound to an RNA CUG repeat expansion motif, revealing binding interactions and conformational changes that inform drug design.