Growth Factor-Independent mTORC1 Signaling Promotes Primary Cilia Length via Suppression of Autophagy
Jong Shin, Khaled Tighanimine, Yann Cormerais, Dean M. Rosenthal, Pratima Niroula, Samuel C. Lapp, Krystle C. Kalafut, Madi Y. Cissé, Sandra Schrötter, Brendan D. Manning
This study shows mTORC1 signaling promotes primary cilia elongation by suppressing autophagy, with effects observed in mouse neurons.
iScience · Nov 25, 2025Peer-reviewedCell Biology