Author

Deborah Kaback

UConn Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Siu‐Pok YeeiD· 4 shared Laurinda A. JaffeiD· 2 shared Adeel AhmadiD· 1 shared C. M. OweniD· 1 shared Caroline N. DealyiD· 1 shared Chuzhao LeiiD· 1 shared Fouad Lemtiri‐ChliehiD· 1 shared Giulia VigoneiD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

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10 top collaborators · 18 mutual co-author links

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4 shared papersDevelopmental Biology

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4 papers

Recent·Most cited

Conditional replacement of the mouse LH receptor with GFP, enabling imaging of cell migration during ovulation

C. M. Owen, Katie M. Lowther, Deborah Kaback, Laurinda A. Jaffe, Siu‐Pok Yee

This paper describes a mouse line enabling conditional replacement of the LHR with GFP to study cell migration during ovulation.

Endocrinology · May 26, 2026Peer-reviewedDevelopmental Biology

Bovine Formative Embryonic Stem Cell Plasticity in Embryonic and Extraembryonic Differentiation

Yue Su, Ruifeng Zhao, Yifei Fang, Meiao Renxiu, Guangsheng Li, Liangliang Jin, Jiaxi Liu, Zhen Yang, Ningxiao Li, Jiaqi Zhu, Neha Mishra, Deborah Kaback, Siu Pok Yee, Yan Luo, Wenjing Wan, , Xiuchun Tian

This paper generates bovine formative embryonic stem cells with dual developmental plasticity, capable of differentiating into various embryonic and extraembryonic cell types.

Stem Cells · Oct 21, 2025Peer-reviewedDevelopmental Biology

Melatonin Enhances Sleep via MT1-Driven Activation of Slo1 in Suprachiasmatic Nucleus Neurons

Kiranmayi Vedantham, Adeel Ahmad, Longgang Niu, Yuan Shui, Fouad Lemtiri‐Chlieh, Deborah Kaback, Xin‐Ming Ma, Xiangyou Hu, Siu‐Pok Yee, Zhao‐Wen Wang

This study identifies a molecular pathway where melatonin promotes sleep by activating BK channels (Slo1) via MT1 receptors in SCN neurons, revealing a core circadian mechanism for sleep regulation.

bioRxiv · Mar 12, 2025 · PreprintNeuroscience

Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor

Leia C. Shuhaibar, Jerid W. Robinson, Giulia Vigone, Ninna Shuhaibar, Jeremy R. Egbert, Valentina Baena, Tracy F. Uliasz, Deborah Kaback, Siu‐Pok Yee, Robert Feil, Melanie C. Fisher, Caroline N. Dealy, Lincoln Ross Potter, Laurinda A. Jaffe

The paper shows that dephosphorylation of NPR2 reduces cyclic GMP, counteracting bone elongation induced by FGF signaling.

eLife · Dec 4, 2017Peer-reviewedDevelopmental Biology