Siu‐Pok Yee

The paper validates a two-step breeding protocol for generating miR-141/200c conditional knockout mice and shows the importance of removing the lacZ/Neo cassette for normal gene expression.

This paper introduces a novel epitope-tagged knock-in mouse model to study C1QL3 localization and function in the brain.

This paper describes a mouse line enabling conditional replacement of the LHR with GFP to study cell migration during ovulation.

This paper generates bovine formative embryonic stem cells with dual developmental plasticity, capable of differentiating into various embryonic and extraembryonic cell types.

This study identifies a molecular pathway where melatonin promotes sleep by activating BK channels (Slo1) via MT1 receptors in SCN neurons, revealing a core circadian mechanism for sleep regulation.

This study shows that an autism-associated ASPM mutation causes macrocephaly and social-cognitive deficits in mice by altering the excitatory-inhibitory neuron ratio.

This study creates a mouse model with a patient-derived NLGN2 R215H mutation, showing GABAergic deficits and schizophrenia-like behaviors.

The paper shows that dephosphorylation of NPR2 reduces cyclic GMP, counteracting bone elongation induced by FGF signaling.