Author

Denise Campobasso

Agostino Gemelli University Polyclinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Clara Di MarioiD· 3 shared Domenico SommaiD· 3 shared Jack FrewiD· 3 shared Lavinia Agra ColettoiD· 3 shared Luca PetriccaiD· 3 shared Lucy MacDonaldiD· 3 shared Maria Antonietta D’AgostinoiD· 3 shared Maria Rita GiganteiD· 3 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Clara Di MarioORCID

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Author profile →

3 papers

Recent·Most cited

Synovial lining expressed mechanosensor PIEZO1 drives inflammation-permissive macrophage phenotypes and joint inflammation

Theodoros Simakou, Marcus Doohan, Carmen Huesa, Kieran Woolcock, Domenico Somma, Watipenge Harmony Nyasulu, Shreya Prakash, Kieran A. Boyle, Luxin Yang, Binghua Darren Zhang, Denise Campobasso, Clara Di Mario, Andrew Farthing, Jack Frew, Lavinia Agra Coletto, , Mariola Kurowska‐Stolarska

This study identifies PIEZO1 as a mechanosensor driving inflammation-permissive macrophage phenotypes in synovial tissue, contributing to joint inflammation in RA.

bioRxiv · Jan 13, 2026 · PreprintImmunology

The ontogeny of myeloid-stromal synovial tissue niches in rheumatoid arthritis.

Aziza Elmesmari, Domenico Somma, Lucy MacDonald, Jack Frew, Zuzanna Kuczynska, Clara Di Mario, Lavinia Agra Coletto, Shravani Baruah, Denise Campobasso, Theodoros Simakou, Eva M.L. Philippon, Sander W. Tas, Marcus Doohan, Roberta Benvenuto, Dario Bruno, , Mariola Kurowska‐Stolarska

This study shows human synovial tissue-resident macrophages develop from monocytes guided by fibroblast-derived cues in specific spatial niches, using a novel organoid system.

bioRxiv · Oct 29, 2025 · PreprintImmunology

Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis

Lucy MacDonald, Aziza Elmesmari, Domenico Somma, Jack Frew, Clara Di Mario, Roopa Madhu, Audrey Paoletti, Theodoros Simakou, Olympia M Hardy, Barbara Tolusso, Denise Campobasso, Simone Perniola, Marco Gessi, Maria Rita Gigante, Luca Petricca, , Mariola Kurowska‐Stolarska

This study identifies distinct myeloid DC subsets in synovial tissue across health and RA states, showing their roles in inflammation and tolerance.

Immunity · Nov 27, 2024Peer-reviewedImmunology