Olympia M Hardy

The paper analyzes scRNAseq data from multiple tissues to identify shared and tissue-specific myeloid and stromal cell populations in health and disease.

CellDEEP improves differential gene expression analysis in scRNA-seq by aggregating cells into metacells, reducing false positives and increasing true positives compared to single-cell and pseudobulk methods.

This study shows that PROS1 released by lung basal cells during SARS-CoV-2 infection reduces inflammation, promotes epithelial repair, and enhances antigen presentation.

This study identifies distinct myeloid DC subsets in synovial tissue across health and RA states, showing their roles in inflammation and tolerance.

This study uses spatial transcriptomics to analyze gene expression changes in the small intestine of H. polygyrus-infected mice, identifying altered signaling pathways and cell interactions during infection.