Author

Denise Posadas Pena

Universität Ulm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:zebrafish· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Gilbert WeidingeriD· 4 shared Chiara BongiovanniiD· 2 shared Gabriele D’UvaiD· 2 shared Hossein Falah MohammadiiD· 2 shared Simone Redaelli· 2 shared Arica BeisawiD· 1 shared Carlo VenturaiD· 1 shared Carmen MianoiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersDevelopmental Biology

Gilbert WeidingerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Wnt/β-catenin signaling promotes zebrafish osteoblast dedifferentiation by wnt10a-mediated inhibition of NF-κB

Hossein Falah Mohammadi, Denise Posadas Pena, Dila Gulensoy, Ivonne M. Sehring, Gilbert Weidinger

The paper shows that Wnt/β-catenin signaling via wnt10a inhibits NF-κB to induce osteoblast dedifferentiation in zebrafish, which is also observed in cardiomyocytes during heart regeneration.

bioRxiv · Dec 29, 2025 · PreprintDevelopmental Biology

A balanced circadian glycolytic rhythm drives cardiomyocyte cell cycle progression during fish heart regeneration.

Gennaro Ruggiero, Rita Alonaizan, William T. Stockdale, Konstantinos Lekkos, Denise Posadas Pena, Vanessa Obi, Jun Ying, Sara Al‐Dahwi, John Walsby-Tickle, Madeleine E. Lemieux, Gilbert Weidinger, Mathilda T.M. Mommersteeg

This study shows that circadian rhythms in glycolysis and cell cycle progression are essential for cardiomyocyte proliferation and heart regeneration in zebrafish.

bioRxiv · Sep 15, 2025 · PreprintPhysiology

BMP signaling promotes heart regeneration via alleviation of replication stress

Mohankrishna Dalvoy Vasudevarao, Denise Posadas Pena, Michaela Ihle, Chiara Bongiovanni, Pallab Maity, Simone Redaelli, Kathrin Happ, Dominik Geissler, Hossein Falah Mohammadi, Melanie Rall-Scharpf, Chi-Chung Wu, Arica Beisaw, Karin Scharffetter‐Kochanek, Gabriele D’Uva, Lisa Wiesmüller, Gilbert Weidinger

This study shows BMP signaling alleviates replication stress in cardiomyocytes, enabling heart regeneration in zebrafish and potentially applicable to humans.

bioRxiv · May 24, 2024 · PreprintDevelopmental Biology

BMP7 promotes cardiomyocyte regeneration

Chiara Bongiovanni, Hanna Bueno-Levy, Denise Posadas Pena, Irene Del Bono, Carmen Miano, Stefano Boriati, Silvia Da Pra, Francesca Sacchi, Simone Redaelli, Max D. Bergen, Donatella Romaniello, Francesca Pontis, Riccardo Tassinari, Laura Kellerer, Ilaria Petraroia, , Gabriele D’Uva

This study identifies BMP7 as a key growth factor promoting cardiomyocyte proliferation in both mouse and zebrafish models, with potential therapeutic applications for heart regeneration.

Cell Reports · Apr 27, 2024Peer-reviewedMolecular Biology