Arica Beisaw

Junb acts downstream of the Il-11/Stat3 signaling axis to limit tissue damage induced fibro-inflammation during regeneration

This study identifies Junb as a regulator of inflammation during regeneration, showing that its loss leads to fibroinflammatory damage and impaired regeneration in zebrafish.

FYCO1 improves postischemic cardiac remodeling via enhanced autophagic flux and attenuation of proinflammatory signaling

This study identifies FYCO1 as a regulator of autophagy that improves cardiac remodeling after myocardial infarction by enhancing autophagic flux and reducing inflammation.

Cardiomyocyte autophagy promotes a pro-regenerative immune response during cardiac regeneration

This study shows that cardiomyocyte autophagy promotes a pro-regenerative immune response by modulating macrophage gene expression during zebrafish cardiac regeneration.

Border-zone cardiomyocytes and macrophages contribute to remodeling of the extracellular matrix to promote cardiomyocyte invasion during zebrafish cardiac regeneration

This study identifies border-zone cardiomyocytes and macrophages as key contributors to ECM remodeling that facilitates cardiomyocyte invasion during zebrafish cardiac regeneration.

BMP signaling promotes heart regeneration via alleviation of replication stress

This study shows BMP signaling alleviates replication stress in cardiomyocytes, enabling heart regeneration in zebrafish and potentially applicable to humans.

Genome-wide strategies reveal target genes of Npas4l associated with cardiovascular development in zebrafish

The paper identifies Npas4l target genes involved in cardiovascular development using zebrafish models and genome-wide approaches.