Author

Silvia Da Pra

University of BolognaORCID 0000-0001-6906-2806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Carlo VenturaiD· 3 shared Carmen MianoiD· 3 shared Chiara BongiovanniiD· 3 shared Francesca SacchiiD· 3 shared Gabriele D’UvaiD· 3 shared Irene Del Bono· 3 shared Mattia LauriolaiD· 3 shared Riccardo TassinariiD· 3 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Carlo VenturaORCID

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3 papers

Recent·Most cited

Hierarchical and context-dependent GR-MR signalling governs endogenous corticosteroid decoding in the heart

Francesca Sacchi, Stefano Boriati, Rocco Caliandro, Silvia Da Pra, Irene Del Bono, Azra Husetić, Chiara Bongiovanni, Carmen Miano, Nicola Pianca, Silvia Mazzone, Alice Cabrini, Riccardo Tassinari, Carlo Ventura, Mattia Lauriola, Monika M Gladka, Gabriele D’Uva

This study shows that corticosteroid responses in the heart are governed by a hierarchical GR-MR signaling mechanism and cellular context, with GR restraining MR output and influencing cardiomyocyte proliferation and fibroblast activation.

bioRxiv · Sep 11, 2026 · PreprintMolecular Biology

Harnessing glucocorticoid receptor antagonization to enhance the efficacy of cardiac regenerative growth factors and cytokines

Silvia Da Pra, Stefano Boriati, Carmen Miano, Francesca Sacchi, Christopher A. P. Batho, Chiara Bongiovanni, Irene Del Bono, Alla Aharonov, Nicola Pianca, Riccardo Tassinari, Rowda Dahir, Carlo Ventura, Mattia Lauriola, Eldad Tzahor, Catherine H. Wilson, Gabriele D’Uva

This paper shows that blocking glucocorticoid receptors enhances the effectiveness of growth factors in promoting cardiac regeneration by restoring MAPK/ERK signaling in cardiomyocytes.

Nature Cardiovascular Research · Feb 6, 2026Peer-reviewedCell Biology

BMP7 promotes cardiomyocyte regeneration

Chiara Bongiovanni, Hanna Bueno-Levy, Denise Posadas Pena, Irene Del Bono, Carmen Miano, Stefano Boriati, Silvia Da Pra, Francesca Sacchi, Simone Redaelli, Max D. Bergen, Donatella Romaniello, Francesca Pontis, Riccardo Tassinari, Laura Kellerer, Ilaria Petraroia, , Gabriele D’Uva

This study identifies BMP7 as a key growth factor promoting cardiomyocyte proliferation in both mouse and zebrafish models, with potential therapeutic applications for heart regeneration.

Cell Reports · Apr 27, 2024Peer-reviewedMolecular Biology