Anti-MDA5 monoclonal antibodies from patients with dermatomyositis - B cell characteristics and differential targeting of the helicase domains
Eveline Van Gompel, Marina Galesic, Nicolas Delaroque, Karolin Kern, Ragnhild Stålesen, Antonella Notarnicola, Deniz Demirdal, Monika Hansson, Annika van Vollenhoven, Edvard Wigren, S. Gräslund, Michael Szardenings, Vivianne Malmström, Ingrid E. Lundberg, Begum Horuluoglu, , Vijay Joshua
The paper identifies anti-MDA5 monoclonal antibodies from DM patients, showing they target distinct epitopes within the helicase domains of MDA5.
Journal of Autoimmunity · Feb 19, 2026Peer-reviewedImmunology