Author

Marina Galesic

Karolinska University HospitalORCID 0009-0001-1245-1402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Antonella NotarnicolaiD· 2 shared Begum HoruluogluiD· 2 shared Caroline GrönwalliD· 2 shared Eveline Van GompeliD· 2 shared Ingrid E. LundbergiD· 2 shared Vijay JoshuaiD· 2 shared A. Maeda· 1 shared Akiko Shimazaki-Takahashi· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Antonella NotarnicolaORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 31, 2026

✦ In-depth digest

MDA5 multimerization on LINE RNA drives pathogenic extracellular immune complexes in autoimmunity

T. Hsu, Xi Wang, Jiayan Zhang…·Sun Hur

Patient-derived anti-MDA5 antibodies bind MDA5 filaments in two germline-encoded modes; only filament immune complexes activate innate immunity, with LINE-derived dsRNA scaffolding circulating filaments in patient plasma.

DOI 10.64898/2026.01.27.702129

humanprotein structure

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ImmunologyJournal of AutoimmunityPeer-reviewedFeb 19, 2026

Anti-MDA5 monoclonal antibodies from patients with dermatomyositis - B cell characteristics and differential targeting of the helicase domains

Eveline Van Gompel, Marina Galesic, Nicolas Delaroque…·Vijay Joshua

The paper identifies anti-MDA5 monoclonal antibodies from DM patients, showing they target distinct epitopes within the helicase domains of MDA5.

4 citationstop 1%

humanproteomics

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ImmunologyCellPeer-reviewedJan 1, 2026

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Anoctamin-2-specific T Cells Link Epstein-Barr Virus to Multiple Sclerosis

Olivia G. Thomas, Urszula Rykaczewska, Marina Galesic…·Tomas P Olsson

CD4+ T cells cross-reactive between Epstein-Barr virus EBNA1 and the central nervous system channel anoctamin-2 (ANO2) are elevated in multiple sclerosis and exacerbate experimental autoimmune encephalomyelitis in mice.

40 citationstop 1%

humanmouse

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