Hippocampal hyperactivity in a rat model of Alzheimers disease
Liudmila Sosulina, Manuel Mittag, Hans‐Rüdiger Geis, Kerstin Hoffmann, Igor V. Klyubin, Yingjie Qi, Julia Steffen, Detlef Friedrichs, Niklas Henneberg, Falko Fuhrmann, Daniel Justus, Kevin Keppler, A. Claudio Cuello, Michael J. Rowan, Martin Fuhrmann, Stefan Remy
The paper investigates hippocampal neuronal activity in a rat Alzheimer's disease model, finding hyperactivity and intrinsic excitability changes in CA1 neurons before synaptic inhibition is affected.
Journal of Neurochemistry · Feb 14, 2021Peer-reviewedNeuroscience