Author

Kevin Keppler

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Organism:rat· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Julia SteffeniD· 3 shared Martin FuhrmanniD· 3 shared Lena Christine Justus· 2 shared Manuel MittagiD· 2 shared A. Claudio CuelloiD· 1 shared Christian KurtsiD· 1 shared Cornelia Hoyer· 1 shared Daniel JustusiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Julia SteffenORCID

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3 papers

Recent·Most cited

CX3CR1 modulates migration of resident microglia towards brain injury

Jens Wagner, Cornelia Hoyer, Henrike Antony, Kristiina Lundgrén, Rabah Soliymani, Sophie Crux, Lena Christine Justus, Kevin Keppler, Julia Steffen, Christian Kurts, Daniel Robert Engel, Jochen Wolfgang Herms, Maciej M. Lalowski, Martin Fuhrmann

This study shows that CX3CR1 deficiency enhances microglial migration towards brain injury, suggesting it as a potential therapeutic target for CNS injuries.

bioRxiv · Sep 23, 2024 · PreprintNeuroscience

Microglia motility depends on neuronal activity andpromotes structural plasticity in the hippocampus

Felix Christopher Nebeling, Stefanie Poll, Lena Christine Justus, Julia Steffen, Kevin Keppler, Manuel Mittag, Martin Fuhrmann

This study shows that microglia motility depends on neuronal activity and promotes synaptic plasticity in the hippocampus of awake mice.

eLife · Feb 7, 2023Peer-reviewedNeuroscience

Hippocampal hyperactivity in a rat model of Alzheimers disease

Liudmila Sosulina, Manuel Mittag, Hans‐Rüdiger Geis, Kerstin Hoffmann, Igor V. Klyubin, Yingjie Qi, Julia Steffen, Detlef Friedrichs, Niklas Henneberg, Falko Fuhrmann, Daniel Justus, Kevin Keppler, A. Claudio Cuello, Michael J. Rowan, Martin Fuhrmann, Stefan Remy

The paper investigates hippocampal neuronal activity in a rat Alzheimer's disease model, finding hyperactivity and intrinsic excitability changes in CA1 neurons before synaptic inhibition is affected.

Journal of Neurochemistry · Feb 14, 2021Peer-reviewedNeuroscience