Author

Igor V. Klyubin

Trinity College DublinORCID 0000-0002-0733-8528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:cell-cell communication· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Michael J. RowaniD· 2 shared A. Claudio CuelloiD· 1 shared Daniel JustusiD· 1 shared Detlef Friedrichs· 1 shared Dominic M. WalshiD· 1 shared Emily Coode· 1 shared Falko Fuhrmann· 1 shared Frederick J. LiveseyiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Michael J. RowanORCID

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2 papers

Recent·Most cited

Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region

Tomáš Ondrejčák, Neng‐Wei Hu, Emily Coode, Tom Campbell, Grant T. Corbett, Ivan Doykov, Kevin A. Mills, Dominic M. Walsh, Frederick J. Livesey, Michael J. Rowan, Igor V. Klyubin

This study shows that extracellular tau's synaptotoxic effects are mediated by its microtubule-binding region, and targeting this region can reverse synaptic plasticity disruption.

Acta Neuropathologica · Jun 2, 2025Peer-reviewedNeuroscience

Hippocampal hyperactivity in a rat model of Alzheimers disease

Liudmila Sosulina, Manuel Mittag, Hans‐Rüdiger Geis, Kerstin Hoffmann, Igor V. Klyubin, Yingjie Qi, Julia Steffen, Detlef Friedrichs, Niklas Henneberg, Falko Fuhrmann, Daniel Justus, Kevin Keppler, A. Claudio Cuello, Michael J. Rowan, Martin Fuhrmann, Stefan Remy

The paper investigates hippocampal neuronal activity in a rat Alzheimer's disease model, finding hyperactivity and intrinsic excitability changes in CA1 neurons before synaptic inhibition is affected.

Journal of Neurochemistry · Feb 14, 2021Peer-reviewedNeuroscience